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ATRA-PLGA NPs could target and be delivered to THP-1 cells in large quantities, leading to inhibition of H37Ra MTB proliferation in macrophages in a dose-dependent manner
it does not establish clinical suitability, consumer safety, or any non-research application
10.1016/s0015-0282(01)02892-8 35 FengN.FengH.WangS.PunekarA
Methyltransferases DNMT1 , a key factor for maintenance of DNA methylation, and DNMT3A , facilitating both de novo and maintenance of DNA methylation, were upregulated while TET1 , which plays a key role in active de-methylation, was downregulated in cardiac MTs (Fig
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