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For context, the CSF exposure of monoclonal antibodies used in Alzheimers disease typically ranges from 0.1% to 0.3% of plasma concentrations, whereas small-molecule CNS drugs often exceed 5%, placing semaglutide within a low but pharmacologically plausible exposure range
Is oral semaglutide (the Wegovy pill) as effective as the injection
Lyophilized peptides are hygroscopic, meaning they readily absorb moisture from the surrounding environment
Meanwhile, drug company researchers are working on new types of GLP-1s that come in pill form that dont require patients to inject themselves with the medication
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