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Composed of 23 amino acids in a D-amino acid configuration, this cell-penetrating peptide represents a novel therapeutic approach to addressing cellular senescence, a fundamental driver of aging and age-related diseases
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On the day of the assay, serial dilutions (7-fold dilutions, 7 concentrations per compound and one well containing only assay buffer) of test compounds were performed in duplicate in assay buffer to appropriate concentrations in 96-well plates (Greiner, U-shape #GR-650201) using a Biomek i7 liquid handler
This decline coincides with many of the visible and physical signs of aging
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