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The thiolase reaction is catalyzed by the ACAA2 encoded enzyme (see the Table below) which is also referred to as medium-chain 3-ketoacyl-CoA thiolase, MCKAT
This makes it particularly useful for individuals exposed to high levels of stress, environmental pollutants, or those recovering from illness
That is precisely why the documented starting dose is a conservative 2 mg once weekly and why the escalation is unhurried the ladder is calibrated to the combined receptor load, not to any one arm
Glucagon-like peptide
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