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Gonzalez-Rellan showed that semaglutide reversed MASH in mice that lacked the brain receptors controlling appetite, demonstrating that weight loss is not required for liver benefits
Continuous, daily usage without breaks is generally not recommended due to the lack of extensive human data and potential risks 1 2
This is why many injectable medications are sold in tinted pens or why it is recommended to keep vials in their original cardboard boxes
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