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Regulation of Intestinal Growth and Response Injury GLP-1R Interestingly, Gcgr / mice have increased circulating GLP-1 and GLP-2 ( Gcgr / mice have significantly increased small and large intestinal length and weight due to the elevated levels of gut-derived hormones (Koehler et al., 2015)

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This suggests that NR4a1 knockdown alters myocardial energy substrate utilization in response to the energy demands of pathological cardiac remodeling