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Albiglutide was somewhat less potent in receptor activation (its a large molecule, ~72 kDa), and required a larger dose (3050 mg weekly)
GLP-1 signaling is the cellular communication process activated when GLP-1 hormone binds to receptors throughout your body, coordinating appetite suppression, insulin secretion, and glucose metabolism across multiple organs including the brain, pancreas, and stomach
Inherited thrombophilias like Factor V Leiden, prothrombin G20210A mutation, or antithrombin deficiency multiply the risk further
The dosage of the medication depends on how much weight loss and glycemic control are needed
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