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The AGA did update their guidelines in 2022 and lists semaglutide and liraglutide as first-line options in addition to a couple of others

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Using both SGLT-2 and DPP-4 inhibitors as active comparators strengthened study validity, while register linkage minimized selection and recall bias by ensuring exposures were recorded independently of outcomes

A study published emphasises that a diet rich in whole foods, including fruits, vegetables, whole grains, and lean proteins, can enhance the effectiveness of weight loss medications by improving satiety and reducing caloric intake