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Artemisone and artemiside are potent panreactive antimalarial agents that also synergize redox imbalance in Plasmodium falciparum transmissible gametocyte stages
Researchers observed no adverse events and documented rapid pharmacokinetic clearance PMID: 40131143
In such cases, reduced availability of L-arginine limits its ability to act as a substrate for eNOS, favoring the production of ROS over that of NO (Yang and Ming, 2013)
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