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Common GI Symptoms and Onset Nausea, mild abdominal discomfort, and diarrhea often occur in the first few weeks
ACh regulates Ca 2+ levels and transcription factor expression through muscarinic receptors, while acetylcholinesterase (AChE) promotes the breakdown of ACh
The most rapid weight loss typically occurs between months 2 and 6, as doses escalate into the therapeutic range and the medication full metabolic effects take hold
In 2021, FDA approved Novos Wegovy for chronic weight management
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