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Cruciani RA, Dvorkin E, Homel P, Culliney B, Malamud S, Shaiova L, et al
10.1111/j.1464-5491.2009.02790.x 94 OkaJ
Stanford suggests considering the following alternatives: Phentermine/topiramate ER (which has stronger efficacy and is FDAapproved for long-term use) GLP1 receptor agonists (e.g., semaglutide) Dual GLP1/GIP agonists (e.g., tirzepatide) Naltrexone/bupropion Orlistat in select cases The bottom line on phentermine for weight loss Phentermine can be an effective, affordable option for jump-starting weight loss, especially if you need short-term appetite support and pair it with a healthy diet and exercise
People who experience this kind of hyperpigmentation reaction are unlikely to be able to get and maintain any clearance of this darkness on their thighs unless they can also stop the thighs from overheating and rubbing together
