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Samples were mounted onto glass slides using water as a medium and investigated under a Leica (DMI 6000 CS AFC Bino inverted microscope) TCS SP8 instrument
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Consequently, dual GLP-1/glucagon agonists survodutide, and triple GLP-1/GIP/glucagon agonists retatrutide are not spared gastrointestinal adverse events, as glucagon related pro-emetic signaling may offset any potential tolerability benefits from GIP agonism ( The contribution of amylin-based therapies to gastrointestinal adverse events remains less clear
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