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Foot Ankle Clin 12:553567 Hsieh MJ, Liu HT, Wang CN, Huang HY, Lin Y, Ko YS, Wang JS, Chang VH, Pang JH (2017) Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation
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1) Pro-angiogenic signaling (VEGFR2 Akt eNOS) In cell and animal models, BPC-157 increases VEGFR2 expression/internalization and activates downstream Akt-eNOS signaling, supporting endothelial tube formation and blood-flow recovery after ischemia
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