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BP and Cardiovascular Considerations The Phase 3 program documented modest, transient increases in systolic blood pressure (1.9-2.5 mmHg) and diastolic (1.7-1.8 mmHg) in the 4-6 hours after dosing
First study that showed that the incretin effect is markedly reduced in patients with T2DM
Phosphoribosyl diphosphate (PRPP): biosynthesis, enzymology, utilization, and metabolic significance
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