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In late August 2015, the US FDA issued a warning that drugs like sitagliptin, saxagliptin, linagliptin, alogliptin, and other DPP-4 inhibitors could cause joint pain that can be severe and disabling
The study was registered at ClinicalTrials.gov (NCT03789578)
up to 12 weeks for chronic or post-surgical cases These protocols must be supervised by a licensed provider who can adjust dosing based on clinical response, labs, and patient history
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