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Separate neuron populations within the arcuate nucleus express the precursor of the melanocortin receptor agonist proopiomelanocortin (POMC) and the melanocortin receptor inverse agonist agouti-related protein (AgRP)
That said, individual case reports and patient experiences may vary, and the absence of evidence is not necessarily evidence of absence
Glutathione helps by decreasing melanin production, lightening these dark spots and contributing to a more uniform skin tone
Thus, conservative management should be used in these patients as well
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