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Tissues were obtained through the National Disease Research Interchange (Philadelphia, PA) with approval from the University of Pittsburgh Committee for Oversight of Research and Clinical Training Involving Decedents (CORID)
It decreased the levels of inflammatory mediators associated with the MAPK and NF-B signaling pathways, suggesting its anti-inflammatory features
This is an observed phenomenon where the peptides ability to accelerate cell turnover brings underlying congestion (such as microcomedones or trapped sebum) to the surface more quickly
No controlled human trial has tested MOTS-C with retatrutide
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