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Background: isolation from human plasma The tripeptide that would later be characterized as GHK was first reported in 1973, when Pickart and Thaler observed that a low-molecular-weight fraction of human serum prolonged the survival of cultured normal hepatocytes from regenerating rat liver and stimulated growth in a cultured hepatoma line (Pickart & Thaler, 1973)

Take brain cells, for instance

*Correspondence: Gexin Xiao, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers