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coli, the major Gram negative bacteria in the bowel, had 37% resistance in East South Central US in 2010, and 20% in mid-Atlantic

Urate oxidase agents (e.g., rasburicase, pegloticase) promptly lower serum urate levels in gout and tumor lysis syndrome by catalyzing the transformation of uric acid into soluble allantoin [360]

Mitochondrial ROS, particularly O levels, appeared to be elevated in the hippocampal neurons of the Ube3a m-\p+ mouse model, and CoQ10 analogs could attenuate behavioral deficits in these mice [383, 384]

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