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To accustom mice to water deprivation schedule, male C57BL/6J lean mice were allowed to access to two water bottles for 2 h (10:0012:00) for 5 days
This toll on our states health is also a toll on our economy, costing an estimated $10.7 billion a year, or nearly 2% of state GDP
It has been proposed that overexpression of GPX8 reduces Ca 2+ storage and histamine-induced Ca 2+ release in the endoplasmic reticulum (Yoboue et al., 2017)
In brief, mouse electrocardiography was measured in females [Young ( n = 6), Old Con ( n = 8), and Old mAb ( n = 7)] and males [Young ( n = 5), Old Con ( n = 6), and Old mAb ( n = 5)], using a Visual Sonic Vevo2100 imaging system (FUJIFILM VisualSonics Inc, Toronto, ON)
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