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DISCLOSURES: The authors report no conflicts of interest relevant to the content of this article
Contact your healthcare provider if fatigue persists or significantly affects your day-to-day life
Safety and Tolerability While GLP-2 has shown significant benefits, it is not without potential side effects
References include the SURMOUNT-1 trial publication (Jastreboff et al., New England Journal of Medicine , 2022), the Zepbound prescribing information (Eli Lilly, 2024), the American College of Gastroenterology clinical guidelines on GERD (2022), and Davies et al., Diabetes Care , 2023, on gastric emptying with tirzepatide
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