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Extensive evidence demonstrates that PI3K/Akt is a central regulator of cardiomyocyte function and survival, involving multiple aspects of inflammatory regulation, apoptosis, oxidative stress, and cardiac hypertrophy, and it plays an important regulatory role in the progression of cardiovascular disease (Cheng et al., 2021
10.3390/nu8090552 Nutrients 336 NievesJ
Additionally, GLP-1 acts on receptors in the brain's appetite centres, particularly the hypothalamus, promoting feelings of satiety and reducing food intake
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