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SCFAs, such as acetate (C 2 ), propionate (C 3 ), and butyrate (C 4 ), are critical for epithelial barrier integrity, and anti-inflammatory signaling.Low levels are associated with IBD, cancer, obesity, diabetes, kidney disease, hypertension, liver disease, immune system dysfunction, and neurocognitive conditions
Endurance athletes, like runners or swimmers, seeking to improve stamina and reduce fatigue
This has profoundly impacted patients physical and mental well-being, significantly burdening public health systems and medical infrastructures (Lv et al., 2025)
Type 2 diabetes mellitus and osteoarthritis
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