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In clinical research, people are often described as early responders when they reach around 5% loss by week 12, while others progress more gradually (especially because tirzepatide titration commonly extends beyond 12 weeks)
removed 1,050,295 shares (-100.0%) from their portfolio in Q1 2025, for an estimated $548,884 TWO SIGMA ADVISERS, LP removed 847,300 shares (-100.0%) from their portfolio in Q4 2024, for an estimated $1,076,071 UBS GROUP AG added 698,600 shares (+559.2%) to their portfolio in Q1 2025, for an estimated $365,088 MILLENNIUM MANAGEMENT LLC added 580,088 shares (+659.6%) to their portfolio in Q1 2025, for an estimated $303,153 SHENKMAN CAPITAL MANAGEMENT INC removed 557,118 shares (-100.0%) from their portfolio in Q1 2025, for an estimated $291,149 ARISTEIA CAPITAL, L.L.C
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