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For men, obesity may be associated with: Low testosterone and reduced muscle mass Fertility challenges, including lower sperm count and motility Sexual health issues, such as erectile dysfunction and decreased libido Metabolic conditions, including type 2 diabetes, insulin resistance, and hypertension Sleep apnea and cardiovascular risks, both of which impact long-term health When men lose excess weight, they often see improvements in testosterone levels

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The extra pathway is the main reason researchers expect strong metabolic effects from retatrutide