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Prince M, Bryce R, Albanese E, Wimo A, Rieiro W, et al
Shares of Hims & Hers, an online health and wellness company that sells compounded GLP-1 medications, plummeted 25% on Friday
Phentermine is not approved to treat diabetes and works differently from diabetes medications
Tier 1: Pure GLP-1, injectable, FDA-approved Exenatide (Byetta, Bydureon) Liraglutide (Victoza, Saxenda) Lixisenatide (Adlyxin) Dulaglutide (Trulicity) Semaglutide (Ozempic, Wegovy) Efpeglenatide (Eperzan) Tier 2: Pure GLP-1, oral, FDA-approved Semaglutide (Rybelsus) Orforglipron (Orfoglip) Tier 3: Dual or triple agonist, FDA-approved Tirzepatide (Mounjaro, Zepbound) Retatrutide (Retara) Tier 4: Compounded (not FDA-approved) Compounded semaglutide Compounded tirzepatide Compounded semaglutide + B12 Compounded tirzepatide + B12 The tier system reflects regulatory status, not efficacy
