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Because both molecules are hydrophilic, they are readily soluble in standard aqueous solvents
their evidence comes from rodent and cell-culture research, leaving any muscle-growth claim for these three compounds preliminary and non-human in origin
In a 2024 pilot study, older adults with mild B12 deficiency who supplemented for three months saw significant gains in muscle strength and quality, reaching about the same level as people whose B12 was already healthy
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