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As a selective estrogen receptor modulator (SERM), tamoxifen modulates estrogen signaling by binding to the estrogen receptor (ER) in breast tissue, preventing estrogen-driven transcriptional activation of genes that promote tumor cell growth
Serious risks, including kidney strain, liver issues, allergic reactions, and rare cases of Stevens-Johnson syndrome, are linked to high doses, counterfeit vials, and unsupervised administration
This leads to a reduction in appetite and calorie intake
large thiamine doses can cause severe allergic reactions
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