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A clinical trial at Northwestern University (NCT07207148) is currently investigating GLP-1 agonists specifically in MS patients, and results from randomised trials will be needed to establish whether these medications have genuine disease-modifying effects
The regulation of NHE(1) and NHE(3) activity by angiotensin II is mediated by the activation of the angiotensin II type I receptor/phospholipase C/calcium/calmodulin pathway in distal nephron cells
AA received research grants and lecture or advisory board fees from MSD, AstraZeneca, Novartis, Boehringer Ingelheim, Sanofi, Mediolanum, Janssen, Novo Nordisk, Lilly, Servier and Takeda
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