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In the elongated conformation of the antibody-bound GCGR the -helix of the ECD was roughly perpendicular to the plane of the membrane 22
PLoS ONE 16:e0246157 Jackson EK, Raghvendra DK (2004) The extracellular cyclic AMP-adenosine pathway in renal physiology
Figure 2 shows the weight regain trajectory at different follow-up time points after treatment discontinuation
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