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Reduce dose or frequency if: IGF-1 exceeds the age-adjusted upper limit of normal but the patient is asymptomatic Fasting glucose rises 10 to 25 mg/dL from baseline but remains below 126 mg/dL Mild peripheral edema or joint stiffness appears and does not resolve within 2 weeks Systolic blood pressure rises 5 to 10 mmHg from baseline Discontinue CJC-1295 if: Fasting glucose exceeds 126 mg/dL on two consecutive draws IGF-1 remains above the upper limit of normal despite dose reduction New-onset carpal tunnel syndrome does not resolve after 4 weeks at reduced dose Echocardiogram shows new or worsening left ventricular hypertrophy PSA rises more than 0.75 ng/mL (annualized rate) from baseline Discontinuation should be followed by repeat labs at 4 and 8 weeks to confirm normalization
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BPC 157 has anti-inflammatory and wound-healing effects on a wide range of target tissues and organs, including muscles, tendons, ligaments and the gastrointestinal tract
