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Mechanistically, GHK-Cu has been shown to stimulate collagen and elastin synthesis in dermal fibroblasts, increase decorin (a small proteoglycan that helps regulate collagen organization), and influence matrix metalloproteinases and their inhibitors
While they ideally make estrogen metabolites inactive and ready for phase II, any dysfunction in this phase may also leave them active with potentially harmful results.1 Phase I detoxification readies estrogen metabolites and other fat-soluble molecules through hydroxylation to begin their path of elimination
In the most preferred embodiment, the ingredients are formulated into cream having a viscosity of 35,000 to 45,000 cps (measured on a Brookfield LVT Viscometer with a T/C spindle at 5 rpm) and a specific gravity of 0.9990 to 1.100
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