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5.4 GLP-1s anti-apoptotic effects GLP-1 RAs exhibit strong anti-apoptotic effects by activating the PI3K/Akt pathway, which promotes cell survival by inhibiting pro-apoptotic factors such as Bax and caspase-3, while upregulating anti-apoptotic proteins like Bcl-2 (104106)

An abnormal sense of touch was reported in 8.8% of participants on the 9 mg dose and 20.9% on the 12 mg dose, compared to 0.7% on placebo

The earliest expected approval is late 2027, following completion of the Phase 3 TRIUMPH program

En primer lugar, estos medicamentos reducen el vaciamiento gstrico y pueden disminuir la contractilidad de la vescula, lo que favorece la formacin de clculos