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Cell Biol Int 40:887894
Patients on SFU monotherapy ( n = 142) were randomized after completing a 2-week, single-blind, placebo run-in period
As a long acting GLP-1 RA, semaglutide can translocate to the brain stem, lateral septum (LS), and hypothalamus, interact directly with various GLP-1 receptor subtypes and modulate the activity of neural pathways involved in food intake, reward, and energy expenditure (19, 20)
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