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Common effects include: Nausea Constipation Vomiting Diarrhea Bloating Reduced appetite Less common but serious risks may include: Gallbladder disease Pancreatitis Severe dehydration Patients with certain thyroid cancer histories may not be appropriate candidates for some GLP-1 medications

The medication also affects the vagus nerve and activates GLP-1 receptors throughout your gut, which can intensify sensations and alter how your body perceives hunger and satiety

Until proper human trials are conducted, users are essentially volunteering as test subjects in an uncontrolled experiment with their own bodies.

Some individuals plateau at lower doses with excellent results, while others require higher doses for maximal weight loss