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studies in kidney tissue and in animal models showed a reduction of NF-kB activity after the administration of exendin-4 [43, 44]

Heart failure with preserved ejection fraction: the pathophysiological mechanisms behind the clinical phenotypes and the therapeutic approach

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intravenous administration of glutathione are generally not practical for increasing circulating glutathione for most individuals because this procedure is expensive, requires regular visits to a medical practitioner's office, is unsuitable for children and many adults, and poses the risks of side effects associated with regular injections