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doi: 10.3390/ijms25179302 167 Committee on Carcinogenicity of Chemicals in Food, Consumer Products and the Environment (COC)

3 Necroptosis 3.1 Necroptotic signaling pathway Necroptosis is a highly regulated, lytic form of RCD characterized by swelling of organelle and cellular, rupture of dying cells, and the subsequent release of intracellular contents and cytokines (132)