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Thiamine diphosphate acts as a coenzyme in carbohydrate metabolism, in transketolation reactions, and in the utilization of hexose in the hexose-monophosphate shunt
Research documents its influence on cytoskeletal organization in wound-healing cells and its modulation of growth factor receptor expression, including VEGFR2 and the EGF receptor
The most cited work involved complete surgical transection of the rat Achilles tendon, with reported accelerated healing and visually confirmed reduction in injury dimensions relative to controls
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