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Under adequate antioxidant defense, enzymes such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) neutralize these reactive oxygen species (ROS)

In adults with dietary pyridoxine deficiency (often manifesting as anemia, dermatitis, or neuropathy), a typical regimen is 10 mg to 20 mg of pyridoxine HCl given intramuscularly or intravenously once daily for approximately 3 weeks

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