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In women with IDA, the SHep increase of ~0.4 nM after doses of 100 and 200 mg was much smaller than the SHep increase of ~2 nM (about 1.85 nM after correction for method comparison)28 after doses of 120 mg in non-anemic iron depleted women.8 A potential explanation for the lower increase in SHep in response to oral iron in anemic women compared to iron deficient non-anemic women is that hepatic hepcidin expression is more strongly suppressed by ID and erythropoetic drive

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