Covariates Baseline covariates included age, sex, race, ethnicity, geographic region, index year, T2D history, payer type, prescribers specialty, Charlson Comorbidity Index (CCI) [24, 25], diabetes complication severity index (DCSI) [26, 27], body mass index (BMI), and number of all distinct prescription drugs
For all-cause mortality, the five-year survival probability was 96.9% with GLP-1RAs and 82.3% with insulin/metformin
on rat conduit arteries ex vivo, exenatide was not found to significantly ameliorate triglyceride-induced endothelial dysfunction nor did it exert a potent vasorelaxant effect [89]
Based on current studies, researchers are encouraged to consider the following points when administering DSIP intranasally: The optimal dosing schedule will depend upon the studys methodology and desired outcome