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196,197 Such studies have identified a low-frequency variant of CD300LG that is associated with fasting high-density lipoprotein cholesterol (HDL-C), 198 and a TBC1D4 variant that together are connected to higher fasting glucose levels and reduced insulin sensitivity
FDA Actions Timeline (Last verified May 2026): December 5, 2017: FDA approved Ozempic for Type 2 diabetes based on clinical trial evidence
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