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In practical portfolio terms, Novo is doing what the market rewards: prove the maximal efficacy franchise first in the route with the highest probability of success, then decide whether oral conversion is worth the additional complexity
Source: Neurology Advisor
Recent evidence from in vitro and in vivo studies showed that guggulsterone, a FXR antagonist, lowered plasma TMA/TMAO levels (Gautam et al., 2018)
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