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Celastrol, a widely used antioxidant drug, can reduce ROS accumulation by upregulating the Nrf2/GPX4 axis, thus significantly inhibiting ferroptosis of neurons and oligodendrocytes, thereby promoting the recovery of spinal cord tissue and motor function in rats with SCI
Emulating randomized clinical trials with nonrandomized real-world evidence studies
This shift reduces energy production and increases reliance on anaerobic pathways, leading to muscle fatigue and reduced force production
For other concerns about your treatment, contact your GP or prescribing clinician promptly
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