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Despite lower systemic absorption, it maintains local activity in the gut , offering significant benefits for: Ulcers and acid damage Leaky gut and intestinal inflammation NSAID-induced GI injury Key features: Shorter systemic half-life (~24 hours) Strong local effect on gastric mucosa Best used for digestive repair and mucosal protection Which Clears Faster
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Jirillo, E., Altamura, M., Munno, I., Pellegrino, N
Cells 11(5):848 Douros JD, Mokrosinski J, Finan B et al (2024) The GLP-1R as a model for understanding and exploiting biased agonism in next-generation medicines
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