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A key hypothesis we are studying here is that in endometriosis, a pro-oxidant microenvironment in the local vicinity of the follicle created by an unbalanced redox state detrimentally impacts the quality of oocytes, sperm, and embryos, hampering their cellular function, jeopardizing their viability, and that this is a fundamental underlying cause of diminished fertility with endometriosis
Redox-active vitamin C suppresses human osteosarcoma growth by triggering intracellular ROS-iron-calcium signaling crosstalk and mitochondrial dysfunction
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The pharmaceutical formulation may comprise more than 75% w/w water, such as 80% w/w water, such as about 85% w/w water, such as up to 90% w/w water
