These agents work through several complementary mechanisms that improve metabolic control
Potential Side Effects While there are no large randomized controlled studies in the injectable dosage form, some common side effects reported are injection site reactions, nausea, diarrhea, dizziness, fishy body odor, and headache
If you notice adverse effects (e.g., increased nighttime awakenings, headaches, mood shifts, altered blood pressure, hormonal imbalance) reduce dose or discontinue and consult a qualified specialist
Significant weight loss from retatrutide may alter SHBG levels, shifting free-to-total testosterone ratios and potentially requiring dose adjustments in those on testosterone replacement therapy