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For the bioanalysis of SNAC, an LC-MS/MS assay was used following in-line solid-phase sample preparation (validated according to current guidelines for bioanalysis of plasma samples in the concentration range 5.00 to 2000 ng/mL, including extension of the assay range 5-fold by dilution) (Celerion Switzerland AG, Fehraltorf, Switzerland)

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Each domain was rated as High, Low or Some concerns depending on the judgement of each author following the recommendations

This class is powerful because it influences appetite, digestion, and blood sugar at the same time