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Many DSIP failures trace back to incorrect mixing that either destroys the peptide or makes precise dosing impossible
If eight weeks produced no functional improvement, extending the course is less useful than revisiting the diagnosis
The resulting stress may affect mitochondrial energy, antioxidant defense, neurotransmitter regulation, sleep, cognition and medication tolerance
High levels of intracellular amino acids activate mTORC1, and, in turn, mTORC1 activation regulates amino acid availability through downstream signaling effectors (Figure 2)
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