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It is found that in the clinical follow-up studies of NAFLD patients, compared with the control group, hepatic fat content and ALT levels were not significantly reduced in Lira group and were associated with an increased incidence of gastrointestinal adverse events [118]

Another option is Low Dose Naltrexone (LDN), an off-label therapy that modulates immune function and can be particularly beneficial in reducing chronic inflammation, especially in autoimmune or neuroinflammatory conditions

It is FDA-approved to control blood sugar levels in people with type 2 diabetes, in combination with diet and exercise

Of the patients in the semaglutide group, 86.4% had a weight reduction of at least 5%, 69.1% had a weight reduction of 10% or more, and 10.5% lost at least 15% of their body weight